Dr Gerry Coghlan

MB BCH BAO MD MRCPI FRCP(LON)

Consultant Cardiologist

Dr Coghlan qualified from University College Dublin in 1983. He trained in cardiology at the National Cardiac Centre (Baggot Street) Dublin, Harefield Hospital and The Royal Free Hospital. He was appointed consultant cardiologist at the Royal Free Hospital in 1997. He is a founder member of the National Pulmonary Hypertension Physicians Association and has developed the Royal Free National Pulmonary Hypertension Service, with a particular interest in connective tissue disease associated PHT.

He has developed an ‘outreach’ model for pulmonary hypertension care attending clinics at Guys & St Thomas’ Hospital, Kings College Hospital, Royal United Hospital Bath, Derriford Hospital Plymouth, Queen Alexandra Hospital Portsmouth and Ulster Hospital Dundonald. From 1999, he was clinical lead in cardiology with the Regional Health Authority, lead for the North Central Sector collaborative program from 2002 – 2004 and from August 2004 – 2013 medical chair of the North Central Sector Cardiac Network.

In addition he was the Head of Service for medical specialties in the Royal Free Hospital from 2001, clinical director of acute medical specialties from July 2004 and Deputy director for medical specialties 2005 – 2009. With the advent of UCL partners he is now leading a group to co-ordinate pulmonary hypertension services & research across 4 hospitals linked to UCL and cardiology lead for the BAMS (BA in medical sciences) course at the Royal Free Site. He is currently governance lead for the Cardiology Service at the Royal Free Hospital.

Hospital Locations

Royal Free Hospital

Specialities

Cardiology

Procedures offered

Right Heart catheterisation, pulmonary angiography & vasodilator testing
Cardiac catheterisation (radial & femoral)
Coronary angioplasty, stenting, intracoronary imaging, rotablation
Pacemaker Implantation
Cardioversion
Hickman/Groshong line insertion & management
Endomyocardial biopsy

Clinical interests

Interventional cardiology/angioplasty
Ischaemic heart disease
Hypertension
Pulmonary hypertension
Cardiac involvement in connective tissue disease
Breathlessness
Syncope
Chest pain

Special interests

Pulmonary hypertension
Connective tissue and heart disease
Angioplasty
Interventional and general cardiology care
Cardiac lead for the North Central cardiovascular network. Provides clinics at leading hospitals in south England and Belfast

Research interests

Principle investigator for many studies in the fields of pulmonary hypertension, cardiac imaging, ischaemic heart disease, including multinational studies.

Published papers

Over 100 published papers – last 5 years shown:
2015 “Knight, Daniel S.; Schwaiger, Johannes P.; Krupickova, Sylvia; Davar, Joseph; Muthurangu, Vivek; Coghlan, J. Gerry”Accuracy and Test-Retest Reproducibility of Two-Dimensional Knowledge-Based Volumetric Reconstruction of the Right Ventricle in Pulmonary Hypertension. J Am Soc Echocardiogr (ePub)]
2015 “Knight, Daniel S.; Grasso, Agata E.; Quail, Michael A.; Muthurangu, Vivek; Taylor, Andrew M.; Toumpanakis, Christos; Caplin, Martyn E.; Coghlan, J. Gerry; Davar, Joseph”Accuracy and reproducibility of right ventricular quantification in patients with pressure and volume overload using single-beat three-dimensional echocardiography. J Am Soc Echocardiogr 28(3): 363-374
2015 “Quail, Michael Alexander; Knight, Dan S.; Steeden, Jennifer A.; Taelman, Liesbeth; Moledina, Shahin; Taylor, Andrew M.; Segers, Patrick; Coghlan, J. Gerry; Muthurangu, Vivek”Non-Invasive Pulmonary Artery Wave Intensity Analysis in PulmonaryHypertension. Am J Physiol Heart Circ Physiol (ePub)
2014 “Vachiery, Jean-Luc; Adir, Yochai; Barbera, Joan Albert; Champion, Hunter; Coghlan, John Gerard; Cottin, Vincent; De Marco, Teresa; Galie, Nazzareno; Ghio, Stefano; Gibbs, J. Simon R.; Martinez, Fernando; Semigran, Marc; Simonneau, Gerald; Wells, Athol; Seeger, Werner” [Pulmonary hypertension due to left heart diseases]. Turk Kardiyol Dern Ars 42 (Suppl 1): 130-141
2014 “Seeger, Werner; Adir, Yochai; Barbera, Joan Albert; Champion, Hunter; Coghlan, John Gerard; Cottin, Vincent; De Marco, Teresa; Galie, Nazzareno; Ghio, Stefano; Gibbs, Simon; Martinez, Fernando J.; Semigran, Marc J.; Simonneau, Gerald; Wells, Athol U.; Vachiey, Jean-Luc” [Pulmonary hypertension in chronic lung diseases]. Turk Kardiyol Dern Ars 42 (Suppl 1) 142-152
2014 “Olsson, Karen M.; Delcroix, Marion; Ghofrani, H. Ardeschir; Tiede, Henning; Huscher, Doerte; Speich, Rudolf; Grunig, Ekkehard; Staehler, Gerd; Rosenkranz, Stephan; Halank, Michael; Held, Matthias; Lange, Tobias J.; Behr, Juergen; Klose, Hans; Claussen, Martin; Ewert, Ralf; Opitz, Christian F.; Vizza, C. Dario; Scelsi, Laura; Vonk-Noordegraaf, Anton; Kaemmerer, Harald; Gibbs, J. Simon R.; Coghlan, Gerry; Pepke-Zaba, Joanna; Schulz, Uwe; Gorenflo, Matthias; Pittrow, David; Hoeper, Marius M.” “Response to letters regarding article, “”Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA) Circulation 130(12): e110-112
2014 “Hong, C.; Sangle, S. R.; Coghlan, J. G.; D’Cruz, D. P.” Scleroderma and breast implants. QJM (ePub)
2014 “Coghlan, J. Gerry; Denton, Christopher P.; Grunig, Ekkehard; Bonderman, Diana; Distler, Oliver; Khanna, Dinesh; Muller-Ladner, Ulf; Pope, Janet E.; Vonk, Madelon C.; Doelberg, Martin; Chadha-Boreham, Harbajan; Heinzl, Harald; Rosenberg, Daniel M.; McLaughlin, Vallerie V.; Seibold, James R.” Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study. Ann Rheum Dis 73(7): 1340-1349
2014 “Nihtyanova, Svetlana I.; Schreiber, Benjamin E.; Ong, Voon H.; Rosenberg, Daniel; Moinzadeh, Pia; Coghlan, J. Gerrard; Wells, Athol U.; Denton, Christopher P.” Prediction of pulmonary complications and long-term survival in systemic sclerosis. Arthritis Rheumatol 66(6): 1625-1635
2014 “George, Peter M.; Oliver, Eduardo; Dorfmuller, Peter; Dubois, Olivier D.; Reed, Daniel M.; Kirkby, Nicholas S.; Mohamed, Nura A.; Perros, Frederic; Antigny, Fabrice; Fadel, Elie; Schreiber, Benjamin E.; Holmes, Alan M.; Southwood, Mark; Hagan, Guy; Wort, Stephen J.; Bartlett, Nathan; Morrell, Nicholas W.; Coghlan, John G.; Humbert, Marc; Zhao, Lan; Mitchell, Jane A.” Evidence for the involvement of type I interferon in pulmonary arterial hypertension. Circ Res 114(4): 677-688
2014 “Olsson, Karen M.; Delcroix, Marion; Ghofrani, H. Ardeschir; Tiede, Henning; Huscher, Doerte; Speich, Rudolf; Grunig, Ekkehard; Staehler, Gerd; Rosenkranz, Stephan; Halank, Michael; Held, Matthias; Lange, Tobias J.; Behr, Juergen; Klose, Hans; Claussen, Martin; Ewert, Ralf; Opitz, Christian F.; Vizza, C. Dario; Scelsi, Laura; Vonk-Noordegraaf, Anton; Kaemmerer, Harald; Gibbs, J. Simon R.; Coghlan, Gerry; Pepke-Zaba, Joanna; Schulz, Uwe; Gorenflo, Matthias; Pittrow, David; Hoeper, Marius M.” “Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA).” Circulation. 130(12):e110-2.
2014 “Visovatti, Scott H.; Distler, Oliver; Coghlan, J. Gerry; Denton, Christopher P.; Grunig, Ekkehard; Bonderman, Diana; Muller-Ladner, Ulf; Pope, Janet E.; Vonk, Madelon C.; Seibold, James R.; Torres-Martin, Juan-Vicente; Doelberg, Martin; Chadha-Boreham, Harbajan; Rosenberg, Daniel M.; McLaughlin, Vallerie V.; Khanna, Dinesh” Borderline pulmonary arterial pressure in systemic sclerosis patients: a post-hoc analysis of the DETECT study. Arthritis Res Ther Dec 10;16(6):493
2014 “Marder, Liz; Coghlan, J. G.” UK resources in the care of adults with Down’s syndrome. BMJ Oct 21: 349
2013 “Vachiery, Jean-Luc; Adir, Yochai; Barbera, Joan Albert; Champion, Hunter; Coghlan, John Gerard; Cottin, Vincent; De Marco, Teresa; Galie, Nazzareno; Ghio, Stefano; Gibbs, J. Simon R.; Martinez, Fernando; Semigran, Marc; Simonneau, Gerald; Wells, Athol; Seeger, Werner” Pulmonary hypertension due to left heart diseases. J Am Coll Cardiol 62 (25 Suppl D):100-108
2013 “Seeger, Werner; Adir, Yochai; Barbera, Joan Albert; Champion, Hunter; Coghlan, John Gerard; Cottin, Vincent; De Marco, Teresa; Galie, Nazzareno; Ghio, Stefano; Gibbs, Simon; Martinez, Fernando J.; Semigran, Marc J.; Simonneau, Gerald; Wells, Athol U.; Vachiery, Jean-Luc” Pulmonary hypertension in chronic lung diseases. J Am Coll Cardiol 62 (25 Suppl D):109-116
2013 “Coghlan, Gerry” Does left heart disease cause most systemic sclerosis associated pulmonary hypertension? Eur Respir J 42(4): 888-890
2013 Coghlan, J. Gerry Stress echocardiography and Cochin Risk Prediction Score for the prediction of pulmonary arterial hypertension in scleroderma: not yet ready for prime time. Arthritis Rheum 65(9): 2236-2239
2013 “Pulido, Tomas; Adzerikho, Igor; Channick, Richard N.; Delcroix, Marion; Galie, Nazzareno; Ghofrani, Hossein-Ardeschir; Jansa, Pavel; Jing, Zhi-Cheng; Le Brun, Franck-Olivier; Mehta, Sanjay; Mittelholzer, Camilla M.; Perchenet, Loic; Sastry, B. K. S.; Sitbon, Olivier; Souza, Rogerio; Torbicki, Adam; Zeng, Xiaofeng; Rubin, Lewis J.; Simonneau, Gerald” Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med 369(9): 809-818
2013 “Ghofrani, Hossein-Ardeschir; Galie, Nazzareno; Grimminger, Friedrich; Grunig, Ekkehard; Humbert, Marc; Jing, Zhi-Cheng; Keogh, Anne M.; Langleben, David; Kilama, Michael Ochan; Fritsch, Arno; Neuser, Dieter; Rubin, Lewis J.” Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 369(4): 330-340
2013 “Schreiber, Benjamin E.; Connolly, Michelle J.; Coghlan, J. Gerry” Pulmonary hypertension in systemic lupus erythematosus. Best Pract Res Clin Rheumatol 27(3): 425-434
2013 “Dobarro, David; Schreiber, Benjamin E.; Haddock, Jamanda; Mandumula, Sri; Coghlan, John G.” Bochdalek hernia causing pulmonary hypertension. Circulation 127(17): 1837-1839
2013 “Valerio, Christopher J.; Schreiber, Benjamin E.; Handler, Clive E.; Denton, Christopher P.; Coghlan, John G.” Borderline mean pulmonary artery pressure in patients with systemic sclerosis: transpulmonary gradient predicts risk of developing pulmonary hypertension. Arthritis Rheum 65(4): 1074-1084
2013 “Dobarro, David; Schreiber, Benjamin Emmanuel; Handler, Clive; Beynon, Huw; Denton, Christopher P.; Coghlan, John Gerard” “Clinical characteristics, haemodynamics and treatment of pulmonary hypertension in sarcoidosis in a single centre, and meta-analysis of the published data.” Am J Cardiol 111(2): 278-285
2012 “Ling, Yi; Johnson, Martin K.; Kiely, David G.; Condliffe, Robin; Elliot, Charlie A.; Gibbs, J. Simon R.; Howard, Luke S.; Pepke-Zaba, Joanna; Sheares, Karen K. K.; Corris, Paul A.; Fisher, Andrew J.; Lordan, James L.; Gaine, Sean; Coghlan, J. Gerry; Wort, S. John; Gatzoulis, Michael A.; Peacock, Andrew J.” “Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland.” Am J Respir Crit Care Med 186 (8): 790-796
2012 “Chin, Kelly M.; Coghlan, Gerry” Characterizing the right ventricle: advancing our knowledge. Am J Cardiol 110(6 Suppl):3S-8S
2012 “Majumder, Bikash; Mavroudis, Chrysostomos; Smith, Colette; Coghlan, John G.; Shiu, ManFai; Rakhit, Roby D.” Superior outcome with direct catheter laboratory access vs ED-activated primary percutaneous coronary intervention. Am J Emerg Med 30(7): 1118-1124
2012 “Chighizola, Cecilia; Meroni, Pier Luigi; Schreiber, Benjamin E.; Coghlan, John G.; Denton, Christopher P.; Ong, Voon H.” Role of N-terminal pro-brain natriuretic peptide in detecting clinically significant cardiac involvement in systemic sclerosis patients. Clin Exp Rheumatol 30 (2 Suppl 71): S81-85
2012 “Coghlan, John G.; Schreiber, Benjamin” An update on the evaluation and management of pulmonary hypertension in scleroderma. Curr Rheumatol Rep 14(1):1-10.
2011 “Schreiber, Benjamin E.; Valerio, Christopher J.; Keir, Gregory J.; Handler, Clive; Wells, Athol U.; Denton, Christopher P.; Coghlan, John G.” Improving the detection of pulmonary hypertension in systemic sclerosis using pulmonary function tests. Arthritis Rheum 63(11): 3531-3539
2011 “Condliffe, Robin; Kiely, David G.; Coghlan, J. Gerry; Gibbs, J. Simon R.; Wort, S. John; Corris, Paul A.; Peacock, Andrew J.; Pepke-Zaba, Joanna” Survival in pulmonary hypertension registries: the importance of incident cases. Chest 139(6):1547-8; author reply 1548-1549
2011 “Barst, Robyn J.; Oudiz, Ronald J.; Beardsworth, Anthony; Brundage, Bruce H.; Simonneau, Gerald; Ghofrani, Hossein A.; Sundin, David P.; Galie, Nazzareno” Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension. J Heart Lung Transplant 30(6): 632-643
2010 “Valerio, Christopher J.; Handler, Clive E.; Kabunga, Peter; Smith, Colette J.; Denton, Christopher P.; Coghlan, John G.” Clinical experience with bosentan and sitaxentan in connective tissue disease-associated pulmonary arterial hypertension. Rheumatology (Oxford) 49(11): 2147-2153
2010 “Wilkins, Martin R.; Ali, Omar; Bradlow, William; Wharton, John; Taegtmeyer, Anne; Rhodes, Christopher J.; Ghofrani, Hossein A.; Howard, Luke; Nihoyannopoulos, Petros; Mohiaddin, Raad H.; Gibbs, J. Simon R.” Simvastatin as a treatment for pulmonary hypertension trial. Am J Respir Crit Care Med 181 (10): 1106-1113
2010 “Coghlan,J. Gerry; Pope, Janet; Denton, Christopher P.” Assessment of endpoints in pulmonary arterial hypertension associated with connective tissue disease. Curr Opin Pulm Med 16 (Suppl 1): S27-34
2010 “Barst, Robyn J.; Mubarak, Kamal K.; Machado, Roberto F.; Ataga, Kenneth I.; Benza, Raymond L.; Castro, Oswaldo; Naeije, Robert; Sood, Namita; Swerdlow, Paul S.; Hildesheim, Mariana; Gladwin, Mark T.” Exercise capacity and haemodynamics in patients with sickle cell disease with pulmonary hypertension treated with bosentan: results of the ASSET studies. Br J Haematol 149(3): 426-435
Published books:
Handler C, Coghlan G. Living with Coronary Disease 2007, XVI, 260 p., 17 illus., 14 in colour. ISBN: 978-1-84628-550-9
Abraham, D.; Handler, C.; Dashwood, M.; Coghlan, G. (Eds.) Vascular Complications in Human Disease: Mechanisms and Consequences 2008, Approx. 390 p., 49 illus., 34 in colour. ISBN: 978-1-84628-918-7; Softcover reprint of hardcover 1st ed. 2008 edition (December 10, 2010)
Handler C, Coghlan G. Management of Cardiac Problems in Primary Care (Radcliffe Publishing; 2nd edition 2008) ISBN-10: 1846191440
Handler C, Coghlan G. Preventing Cardiovascular Disease in Primary Care. Radcliffe Medical PR; 2nd edition (August 2008) ISBN-10: 1846191459
Handler C, Coghlan, Brown N. Cardiology in primary care. ISBN-13: 9781857758337
Coghlan G, Handler C. Pulmonary Hypertension: the facts. Oxford University Press 2010 ISBN-13: 9780199582921
Abraham D, Handler C, Dashwood M, Coghlan G (Eds) Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment Springer; 2012 edition (February 7, 2012). ISBN-10: 0857299190
Handler C, Coghlan G. Pulmonary Hypertension. Publisher: Oxford University Press, Oxford: 2012: ISBN-13: 9780199572564 In addition he organises national training and educational conferences & regularly delivers invited lectures at many international meetings (European Society of Cardiology, British Cardiac Society, Euroecho; Britis Society of Echocardiography; EULAR; British Society of Rheumatology).

Dr Gerry Coghlan, Consultant Cardiologist is available to be seen for consultations at Royal Free London

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